Brain simulation as a cloud service

Author(s)

Michael Schirner, Lia Domide, Dionysios Perdikis, Paul Triebkorn, Leon Stefanovski, Roopa Pai, Paula Popa, Bogdan Valean, Jessica Palmer, Chloê Langford, André Blickensdörfer, Michiel van der Vlag, Sandra Diaz-Pier, Alexander Peyser, Wouter Klijn, Dirk Pleiter, Anne Nahm, Oliver Schmid, Marmaduke Woodman, Lyuba Zehl, Jan Fousek, Spase Petkoski, Lionel Kusch, Meysam Hashemi, Daniele Marinazzo, Jean-François Mangin, Agnes Flöel, Simisola Akintoye, Bernd Carsten Stahl, Michael Cepic, Emily Johnson, Gustavo Deco, Anthony R. McIntosh, Claus C. Hilgetag, Marc Morgan, Bernd Schuller, Alex Upton, Colin McMurtrie, Timo Dickscheid, Jan G. Bjaalie, Jochen Mersmann, Viktor Jirsa, Petra Ritter

Abstract

The Virtual Brain (TVB) is now available as open-source cloud ecosystem on EBRAINS, a shared digital research platform for brain science. It offers services for constructing, simulating and analysing brain network models (BNMs) including the TVB network simulator; magnetic resonance imaging (MRI) processing pipelines to extract structural and functional connectomes; multiscale co-simulation of spiking and large-scale networks; a domain specific language for automatic high-performance code generation from user-specified models; simulation-ready BNMs of patients and healthy volunteers; Bayesian inference of epilepsy spread; data and code for mouse brain simulation; and extensive educational material. TVB cloud services facilitate reproducible online collaboration and discovery of data assets, models, and software embedded in scalable and secure workflows, a precondition for research on large cohort data sets, better generalizability and clinical translation.

Organisation(s)

Department of Innovation and Digitalisation in Law

External organisation(s)

Charité – Universitätsmedizin Berlin, S.C. Codemart S.R.L., Aix-Marseille Université, Forschungszentrum Jülich, University Hospital Regensburg, Eidgenössische Technische Hochschule Zürich, Ghent University , San Camillo Hospital, Université Paris Saclay, Ernst Moritz Arndt Universität Greifswald, Deutsches Zentrum für neurodegenerative Erkrankungen, De Montfort University, University Pompeu Fabra, Institució Catalana de Recerca i Estudis Avançats (ICREA), Max-Planck-Institut für Kognitions- und Neurowissenschaften, Monash University, Rotman Research Institut, Universitätsklinikum Hamburg-Eppendorf, Boston University, Swiss National Supercomputing Centre (CSCS), University of Oslo, Codebox Computer-Dienste GmbH, Bernstein Center for Computational Neuroscience Berlin

Journal

NeuroImage

Volume

251

No. of pages

11

ISSN

1053-8119

DOI

https://doi.org/10.1016/j.neuroimage.2022.118973

Publication date

05-2022

Peer reviewed

Yes

Austrian Fields of Science 2012

505002 Data protection

Keywords

ASJC Scopus subject areas

Neurology, Cognitive Neuroscience

Portal url

https://ucrisportal.univie.ac.at/en/publications/2cab78bc-2019-41a6-a829-7107398fb09d